TestMagic

AMAZING GRACE · 05-15-2008, 10:18 PM

Please help me solve this problem.

A 60Kg male patient has been on phenobarbital 15mg TID for several years .His blood level is 7.5mcg/ml which is not in the therapeutic range of
15-40mcg/ml . How do you adjust the dosage to be in the therapeutic range(therapeutic) ? when should be his next blood check ? and how frequent should this pt be monitored?

lara · 05-20-2008, 01:09 AM

New dose= Old dose x Target PDC/Measured PDC
Next blood check should be done in 4-5 hours.
I hope I did answered right.

AMAZING GRACE · 05-21-2008, 02:28 PM

THANK YOU FOR THE RESPONSE .
BUT I STILL NEED AN EXPLANATION ON WHEN THE NEXT CHECK IS.
4-5 HR IS THAT WHEN THE DRUG REACHES THE STEADY STATE CONCENTRATION? HOW DO YOU CALCULATE IT.
AND I AM ASSUMING THAT PDC=IS PLASMA DRUG CONC.

05-15-2008, 10:18 PM	#1 (permalink)
AMAZING GRACE Trying to make mom and pop proud Join Date: Mar 2008 Posts: 2	Phenobarbital Calculation Please help me solve this problem. A 60Kg male patient has been on phenobarbital 15mg TID for several years .His blood level is 7.5mcg/ml which is not in the therapeutic range of 15-40mcg/ml . How do you adjust the dosage to be in the therapeutic range(therapeutic) ? when should be his next blood check ? and how frequent should this pt be monitored?

05-20-2008, 01:09 AM	#2 (permalink)
lara Within my grasp! Join Date: Mar 2005 Posts: 100	New dose= Old dose x Target PDC/Measured PDC Next blood check should be done in 4-5 hours. I hope I did answered right. _ _ _ _ SIG _ _ _ _ lara

Thread Tools
Show Printable Version Email this Page
Display Modes
Linear Mode Switch to Hybrid Mode Switch to Threaded Mode

05-21-2008, 02:28 PM	#3 (permalink)
AMAZING GRACE Trying to make mom and pop proud Join Date: Mar 2008 Posts: 2	THANK YOU FOR THE RESPONSE . BUT I STILL NEED AN EXPLANATION ON WHEN THE NEXT CHECK IS. 4-5 HR IS THAT WHEN THE DRUG REACHES THE STEADY STATE CONCENTRATION? HOW DO YOU CALCULATE IT. AND I AM ASSUMING THAT PDC=IS PLASMA DRUG CONC.

TestMagic

Free GMAT, GRE, SAT Test, TOEFL practice tests