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Re: What is an appropriate time for asking to be removed from waitlists?
I would say that the effect is probably null. As long as they did not give you an offer then the person right after you on the WL is not affected. What matters is the time you will take to reject the potential offer.
The only case where it could be damaging is if you received an offer on April 15th and that the university does not have enough time to make an other offer after your rejection.
I am in the application process too so take my words with caution