PDA

View Full Version : Question from FPGEE for the gurus



jmaisa
11-11-2006, 05:17 PM
Hi,

I am looking at the booklet I got from FPGEE with my exam papers, can somebody please post how to answer it:

The half life of a drug is 9 days. A single 0.5 mg dose of the drug yields an [AUC](infinity sign) value of 408 ng h/mL. In nanograms per milliliter, what plasma level will result at steady state if this product is given once daily and is 77% bio available?

This question is number 41 in the booklet that was sent with the FPGEE exam papers for this year Dec exam.

Any help is highly appreciated.

Maisa

lite
11-11-2006, 10:32 PM
dear maisa
can u post me the file or web site with questions so we can look at it
thanks :)

jmaisa
11-12-2006, 12:06 AM
This is not a question from web site, it is question 41 page 8 from the FPGEE study guide from FPGEC. I figureed out the solution:

cpss = [AUC](infinity)/T(dosing interval, 24 hrs in this case)
The right answer is 408/24=17

Answer C.

try to pass
11-12-2006, 12:13 AM
what if this product is given twice a day?

lite
11-12-2006, 02:21 AM
what if this product is given twice a day?

at this case T= 12 hr