vivyzeta

06-26-2008, 09:56 PM

hi guys,

I was looking at the questions of the old blueprint and I found a couple of ones I am not sure about. Can you please help?

1 The half life of drug is 9 days. A single 0.5 mg dose of the drug yields and AUC value of 408 ng h/ml. In nanogram per milliliters what plasma level will result at steady state if this product is given once day and is 77% bioavailable?

2 the radioactive decay of radium has a rate constant of 4.22 x 10-4 per year. how many years will it take for 20% of the radium initially present to degrade? the amount initially present can be specified as 100%.

3 a solution initially contains methyl acetate 0.01M and NaOH 0.01 M. The solution is unbuffered and both reacting species are consumed. If the rate constant for this reaction at 25 C IS 1.082 L/molexmin, how many minutes will it take for the concentration of methyl acetate to fall to 0.0090 M?

Thanks guys in advance.

Vivi

I was looking at the questions of the old blueprint and I found a couple of ones I am not sure about. Can you please help?

1 The half life of drug is 9 days. A single 0.5 mg dose of the drug yields and AUC value of 408 ng h/ml. In nanogram per milliliters what plasma level will result at steady state if this product is given once day and is 77% bioavailable?

2 the radioactive decay of radium has a rate constant of 4.22 x 10-4 per year. how many years will it take for 20% of the radium initially present to degrade? the amount initially present can be specified as 100%.

3 a solution initially contains methyl acetate 0.01M and NaOH 0.01 M. The solution is unbuffered and both reacting species are consumed. If the rate constant for this reaction at 25 C IS 1.082 L/molexmin, how many minutes will it take for the concentration of methyl acetate to fall to 0.0090 M?

Thanks guys in advance.

Vivi