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Thread: GRE biochemistry, Genetics study group ( GBG ) Join me !

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    GRE biochemistry, Genetics study group ( GBG ) Join me !

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    Hello,

    Let's gather here and start preparing for GRE biochemistry, to exchange ideas, experience and advice. It's very important to do that since there is very little info and materials in the web.

    I'm planning to take the test in October.

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    So I'm starting in this arrangement. First topic will be Genetics and M.Biology. For this I'll be using the principle of Genetics by Snustad and Essential cell biology by Alberts.

    I. MOLECULAR BIOLOGY AND GENETICS 36%
    1. Genetic Foundations
      • Mendelian and non-Mendelian inheritance ( Snustand chapters 3,4,5 )
      • Transformation, transduction and conjugation
      • Recombination and complementation
      • Mutational analysis
      • Genetic mapping and linkage analysis

    2. Chromatin and Chromosomes
      • Karyotypes
      • Translocations, inversions, deletions and duplications
      • Aneuploidy and polyploidy
      • Structure
      • Epigenetics

    3. Genomics
      • Genome structure
      • Physical mapping
      • Repeated DNA and gene families
      • Gene identification
      • Transposable elements
      • Bioinformatics
      • Proteomics
      • Molecular evolution

    4. Genome Maintenance
      • DNA replication
      • DNA damage and repair
      • DNA modification
      • DNA recombination and gene conversion

    5. Gene Expression
      • The genetic code
      • Transcription/transcriptional profiling
      • RNA processing
      • Translation

    6. Gene Regulation
      • Positive and negative control of the operon
      • Promoter recognition by RNA polymerases
      • Attenuation and antitermination
      • Cis-acting regulatory elements
      • Trans-acting regulatory factors
      • Gene rearrangements and amplifications
      • Small non-coding RNA (e.g., siRNA, microRNA)

    7. Viruses
      • Genome replication and regulation
      • Virus assembly
      • Virus-host interactions

    8. Methods
      • Restriction maps and PCR
      • Nucleic acid blotting and hybridization
      • DNA cloning in prokaryotes and eukaryotes
      • Sequencing and analysis
      • Protein-nucleic acid interaction
      • Transgenic organisms
      • Microarray




    II. CELL BIOLOGY 28%Methods of importance to cellular biology, such as fluorescence probes (e.g., FRAP, FRET and GFP) and imaging, will be covered as appropriate within the context of the content below.
    1. Cellular Compartments of Prokaryotes and Eukaryotes: Organization, Dynamics and Functions
      • Cellular membrane systems (e.g., structure and transport across membrane)
      • Nucleus (e.g., envelope and matrix)
      • Mitochondria and chloroplasts (e.g., biogenesis and evolution)

    2. Cell Surface and Communication
      • Extracellular matrix (including cell walls)
      • Cell adhesion and junctions
      • Signal transduction
      • Receptor function
      • Excitable membrane systems

    3. Cytoskeleton, Motility and Shape
      • Regulation of assembly and disassembly of filament systems
      • Motor function, regulation and diversity

    4. Protein, Processing, Targeting and Turnover
      • Translocation across membranes
      • Posttranslational modification
      • Intracellular trafficking
      • Secretion and endocytosis
      • Protein turnover (e.g., proteosomes, lysosomes, damaged protein response)

    5. Cell Division, Differentiation and Development
      • Cell cycle, mitosis and cytokinesis
      • Meiosis and gametogenesis
      • Fertilization and early embryonic development (including positional information, homeotic genes, tissue-specific expression, nuclear and cytoplasmic interactions, growth factors and induction, environment, stem cells and polarity




    III. BIOCHEMISTRY 36%
    1. Chemical and Physical Foundations
      • Thermodynamics and kinetics
      • Redox states
      • Water, pH, acid-base reactions and buffers
      • Solutions and equilibria
      • Solute-solvent interactions
      • Chemical interactions and bonding
      • Chemical reaction mechanisms

    2. Structural Biology: Structure, Assembly, Organization and Dynamics
      • Small molecules
      • Macromolecules (e.g., nucleic acids, polysaccharides, proteins and complex lipids)
      • Supramolecular complexes (e.g., membranes, ribosomes and multienzyme complexes)

    3. Catalysis and Binding
      • Enzyme reaction mechanisms and kinetics
      • Ligand-protein interaction (e.g., hormone receptors, substrates and effectors, transport proteins and antigen-antibody interactions)

    4. Major Metabolic Pathways
      • Carbon, nitrogen and sulfur assimilation
      • Anabolism
      • Catabolism
      • Synthesis and degradation of macromolecules

    5. Bioenergetics (including respiration and photosynthesis)
      • Energy transformations at the substrate level
      • Electron transport
      • Proton and chemical gradients
      • Energy coupling (e.g., phosphorylation and transport)

    6. Regulation and Integration of Metabolism
      • Covalent modification of enzymes
      • Allosteric regulation
      • Compartmentalization
      • Hormones

    7. Methods
      • Biophysical approaches (e.g., spectroscopy, x-ray, crystallography, mass spectroscopy)
      • Isotopes
      • Separation techniques (e.g., centrifugation, chromatography and electrophoresis)
      • Immunotechniques





    II. CELL BIOLOGY 28%Methods of importance to cellular biology, such as fluorescence probes (e.g., FRAP, FRET and GFP) and imaging, will be covered as appropriate within the context of the content below.
    1. Cellular Compartments of Prokaryotes and Eukaryotes: Organization, Dynamics and Functions
      • Cellular membrane systems (e.g., structure and transport across membrane)
      • Nucleus (e.g., envelope and matrix)
      • Mitochondria and chloroplasts (e.g., biogenesis and evolution)

    2. Cell Surface and Communication
      • Extracellular matrix (including cell walls)
      • Cell adhesion and junctions
      • Signal transduction
      • Receptor function
      • Excitable membrane systems

    3. Cytoskeleton, Motility and Shape
      • Regulation of assembly and disassembly of filament systems
      • Motor function, regulation and diversity

    4. Protein, Processing, Targeting and Turnover
      • Translocation across membranes
      • Posttranslational modification
      • Intracellular trafficking
      • Secretion and endocytosis
      • Protein turnover (e.g., proteosomes, lysosomes, damaged protein response)

    5. Cell Division, Differentiation and Development
      • Cell cycle, mitosis and cytokinesis
      • Meiosis and gametogenesis
      • Fertilization and early embryonic development (including positional information, homeotic genes, tissue-specific expression, nuclear and cytoplasmic interactions, growth factors and induction, environment, stem cells and polarity




  3. #3
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    ………………………………………………….


    Last edited by Abualjood; 02-17-2014 at 09:23 PM.

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    Hi Abualjood,
    I am certainly interested in sharing resources and etc on studying if you haven't gotten too far ahead. I also plan to take the test in October.

  5. #5
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    Hey all,

    I'm also planning to take the test in October. Where are you all at in terms of studying? I've been lightly reading and doing practice problems from lehninger principles of biochemistry.. I'd be happy to buckle down and follow a group schedule like the one above. I'm not sure if you both still follow this thread, so I'll direct message you and hopefully we can get an email thread or google doc together to share resources and bounce ideas/questions off each other.

    For anyone else reading this, don't hesitate to message me or reply to this thread to join in - the more the merrier.

    Thanks,
    Sean

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    What material should I follow to take this test.

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    I'm in!

    Heya!
    I live in SF, where are you all studying?? I took the test last month too (Sept) and I think I've covered everything needed for this one but I may be overconfident.

    Let me know!
    Ace

  8. #8
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    Hello everyone, I'm very sorry for not being committed to the thread. I had to postpone my application for this year. I'm planning to take the test next year. If anyone interested in studying online ( at slow rhythm as I'm studying for other exams) please contact me.

    Thank you,

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    Re: GRE biochemistry, Genetics study group ( GBG ) Join me !

    Hi,

    I would like to give this test in this coming september. Would you please help me with the study material? Currently, I am studying Lehninger but I am confused which chapters to read and which not. It would be very helpful if you please tell me the chapters along with the books.

    Thanks

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