Hi,
Can anyone solve the following problem?
A dose of 750 mg of acetaminophen is administered to a patient. A blood sample is drawn one hour after dose administration. The concentration of acetaminophen is measured as 8 mcg/mL (which is 8 mg/L). Acetaminophen has a volume of distribution of 51 L. Determine the total amount of drug remaining in the body 1 hour after dose administration. Do not enter the units, only the number. Round to the nearest whole number.
Following an oral dose of 400 mg of cefpodoxime (Vantin), the terminal elimination rate constant was determined to be 0.38 hr-1, and the AUC was determined to be 25.18 mg x hr/L. Calculate the apparent volume of distribution of cefpodoxime. Do not enter the units, only the number. Round to the nearest whole number.
Please help me, I really don't know how to do this. If anyone know then show me the formula also.
Thanks